Encapsulation, slime production and surface hydrophobicity of coagulase-negative staphylococci

نویسندگان

  • A. H. Hogt
  • J. Dan
  • J. Fei jen
چکیده

Infections associated with prosthetic implants or medical devices are most commonly caused by coagulase-negative staphylococci (CNS) [1]. The ability of CNS to produce slime has been suggested to play a critical role in the adhesion onto surfaces of implants and medical devices [2] and in the course of medical device-associated infections [3]. Staphylococcus aureus, the pathogenic counterpart of CNS, can be encapsulated [4]. Such strains possessed increased virulence in comparison with their non-encapsulated variant strains [5,6]. Characterization of CNS has been advocated [7,8], but no special attention has been given to the presence of a capsule, although encapsulated CNS have been reported [9]. Bacterial adhesion onto surfaces is also regarded to be an important virulence factor [10]. Bacterial interaction with mammalian cells and artificial surfaces is promoted by the hydrophobicity of the bacterial cell surface [11-13]. After characterization of twenty one CNS, the presence of a capsule and the ability to produce extracellular slime were studied. In addition, the surface hydrophobicity of the strains was measured using a xylene-water system [14].

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Slime production and cell surface hydrophobicity of nasopharyngeal and skin staphylococci isolated from healthy people.

The collection of 314 staphylococcal strains including Staphylococcus aureus and coagulase-negative staphylococci (CNS) was isolated from skin or nasopharynx of healthy people. It was found that the majority of staphylococci possessed the ability to produce slime intensively or moderately, irrespective of ecological niche-nose, throat or skin. Most of them showed the hydrophilic cell surface. H...

متن کامل

Extracellular Polysaccharide Production and Biofilm Formation by Coagulase-negative Staphylococci

Coagulase-negative Staphylococci (CoNS) form a part of the skin flora and commonly cause nosocomial bloodstream and catheterrelated infections. According to their relatively low virulence, it is important to detect the virulence factors of clinical isolates. The production of extracellular polymers and formation of biofilms belong to virulence factors. We studied clinical isolates of CoNS and c...

متن کامل

Sequential analysis of staphylococcal colonization of body surfaces of patients undergoing vascular surgery.

Slime-producing coagulase-negative staphylococci are pathogens in vascular surgery by virtue of their ability to adhere to and persist on prosthetic graft material. Inguinal and abdominal skin sites were cultured in 41 patients upon hospitalization, and slime production and antimicrobial susceptibility were assessed in all recovered staphylococcal isolates. Twenty-one patients eventually underw...

متن کامل

Production of slime by coagulase-negative staphylococci (CNS) isolated from clinical and subclinical mastitis in cows.

The aim of the study was to evaluate the slime-producing ability of coagulase-negative staphylococci (CNS) isolated from clinical and subclinical mastitis in cows. The study was carried out on 100 isolates of CNS obtained from milk of 86 cows from farms located in the Lublin region (Poland). Slime-producing ability was observed in over half of coagulase-negative staphylococci (54.0% of isolated...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2002